EGFR-IN-23
Product Specifications
CAS Number
2747133-37-3
Target
EGFR, Others
Related Pathways
JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.05 nM against the BaF3/EGFR-DEL19/T790M/C797S cell line.
Smiles
N(C1=CC(=C(C=C1OC)N2CCC(CN3CCCOCC3)CC2)C=4C=NN(C)C4)C=5N=C(NC6=C(P(C)(C)=O)C7=C(C=C6)N=CC=N7)C(Br)=CN5
Molecular Formula
C36H44BrN10O3P
Molecular Weight
775.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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