EGFR-IN-23
Product Specifications
CAS Number
2747133-37-3
Target
EGFR|||Others
Related Pathways
JAK/STAT signaling|||Others|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.05 nM against the BaF3/EGFR-DEL19/T790M/C797S cell line.
Smiles
N(C1=CC(=C(C=C1OC)N2CCC(CN3CCCOCC3)CC2)C=4C=NN(C)C4)C=5N=C(NC6=C(P(C)(C)=O)C7=C(C=C6)N=CC=N7)C(Br)=CN5
Molecular Formula
C36H44BrN10O3P
Molecular Weight
775.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
M9515-01R 100 µL
Musashi-1 RNA Binding Protein, NT (Musashi 1, Musashi1, Msi1, Msi-1, Musashi Homolog 1, RNA Binding Protein Musashi Homolog 1) discontinued
Ask
View Details 042386-Biotin 200 µL
STAU1, NT (STAU1, STAU, Double-stranded RNA-binding protein Staufen homolog 1) (Biotin) discontinued
Ask
View Details 