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PTP1B-IN-20

Product Specifications

Target

Others|||Phosphatase

Related Pathways

Others|||Metabolism

Bioactivity

PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor with an IC50 of 1.05 ?M, demonstrating selectivity over TCPTP (T-cell protein tyrosine phosphatase) with an IC50 of 78.0 ?M. It targets a crucial enzyme for inhibiting type 2 diabetes, showing preferential action on PTP1B over TCPTP.

Smiles

CC1=C(C=C2C(=C1O)C(=O)C3=C(C2=O)C(=C(C=C3)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO[C@H]5[C@@H]([C@H]([C@@H](CO5)O)O)O)O)O)O

Molecular Formula

C26H28O15

Molecular Weight

580.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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