KIF18A-IN-6
Product Specifications
CAS Number
2914879-10-8
Target
Kinesin, Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Purity
0.9759
Bioactivity
KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor that suppresses KIF18A microtubule-dependent ATPase activity with an IC50 of 0.016 μM. It reduces HCC15 tumour volume in mouse models and may be employed in KIF18A-associated cancer research.
Smiles
O=C(C1=CC=CC(=C1)S(=O)(=O)NC(C)(C)C)N2C3=CC=C(C=C3C4(C2)CCC5(CC4)CC5)NS(=O)(=O)CC
Molecular Formula
C28H37N3O5S2
Molecular Weight
559.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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