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KIF18A-IN-6

Product Specifications

CAS Number

2914879-10-8

Target

Kinesin, Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Purity

0.9759

Bioactivity

KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor that suppresses KIF18A microtubule-dependent ATPase activity with an IC50 of 0.016 μM. It reduces HCC15 tumour volume in mouse models and may be employed in KIF18A-associated cancer research.

Smiles

O=C(C1=CC=CC(=C1)S(=O)(=O)NC(C)(C)C)N2C3=CC=C(C=C3C4(C2)CCC5(CC4)CC5)NS(=O)(=O)CC

Molecular Formula

C28H37N3O5S2

Molecular Weight

559.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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