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CYP1B1-IN-3

Product Specifications

CAS Number

2872575-51-2

Target

Cytochromes P450|||Others

Related Pathways

Others|||Metabolism

Bioactivity

CYP1B1-IN-3 is a potent, selective inhibitor of CYP1B1, exhibiting IC50 values of 6.6 nM for CYP1B1, 347.3 nM for CYP1A1, and >10000 nM for CYP1A2. It also impedes cell migration and invasion, and inhibits the P-gp, AKT/ERK, FAK/SRC, and EMT pathways [1].

Smiles

COc1cc(Nc2nc(-c3nc(-c4ccccc4F)cs3)cs2)cc(OC)c1

Molecular Formula

C20H16FN3O2S2

Molecular Weight

413.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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