STAT3-IN-15
Product Specifications
Target
STAT, Others
Related Pathways
Others, Stem Cells, JAK/STAT signaling
Bioactivity
STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-β1-induced migration and deformation of epithelial cells and prevents epithelial-mesenchymal transition (EMT), offering a multifaceted approach against IPF.
Smiles
C1CN(CCN1CC2=CC(=C(C=C2F)F)F)C(=O)C3=CC4=CC=CC=C4S3(=O)=O
Molecular Formula
C20H17F3N2O3S
Molecular Weight
422.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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