NLRP3-IN-12
Product Specifications
Target
NOD-like Receptor (NLR), Others
Related Pathways
Immunology/Inflammation, Others
Bioactivity
NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome that targets the NLRP3 protein to effectively reduce IL-1β release, with an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease (IBD) .
Smiles
CC1(CC[C@@H]([C@]23[C@@H]1[C@@H]([C@]([C@]45[C@H]2CC[C@H](C4OC(=O)NC6=CC(=CC=C6)Cl)C(=C)C5=O)(OC3)O)O)O)C
Molecular Formula
C27H32ClNO7
Molecular Weight
518
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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