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NLRP3-IN-12

Product Specifications

Target

NOD-like Receptor (NLR) |||Others

Related Pathways

Immunology/Inflammation|||Others

Bioactivity

NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome that targets the NLRP3 protein to effectively reduce IL-1? release, with an IC50 of 0.45 ?M. This compound is utilized in the research of inflammatory bowel disease (IBD) .

Smiles

CC1(CC[C@@H]([C@]23[C@@H]1[C@@H]([C@]([C@]45[C@H]2CC[C@H](C4OC(=O)NC6=CC(=CC=C6)Cl)C(=C)C5=O)(OC3)O)O)O)C

Molecular Formula

C27H32ClNO7

Molecular Weight

518

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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