EIF4A3-IN-9
Product Specifications
CAS Number
1402931-71-8
Target
Others, PERK
Related Pathways
Apoptosis, Others
Bioactivity
EIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It is utilized in researching human cancer pathogenesis [1].
Smiles
O[C@]12[C@]([C@@H]([C@@H](C(OC)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(C(N)=O)C4)C5=CC=C(OC)C=C5
Molecular Formula
C28H27NO8
Molecular Weight
505.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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