HGGPPS-IN-3
Product Specifications
CAS Number
2763223-96-5
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Compound 13h (hGGPPS-IN-3) is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS), characterized as a C-2-substituted thienopyrimidine-based bisphosphonate analogue (C2-ThP-BPs) . It selectively induces apoptosis in multiple myeloma (MM) cells and demonstrates antimyeloma activity in vivo [1].
Smiles
CC1=C(C=C(C=C1)NC(=O)C2=CC=CC(=C2)C3=NC(=C4C=CSC4=N3)NC(P(=O)(O)O)P(=O)(O)O)Br
Molecular Formula
C21H19BrN4O7P2S
Molecular Weight
613.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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