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Falcarindiol

Product Specifications

CAS Number

55297-87-5

Target

JAK|||STAT|||NOD|||NOS

Related Pathways

Tyrosine Kinase/Adaptors|||Immunology/Inflammation|||Stem Cells|||NF-?B|||JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis

Purity

0.9938

Bioactivity

Falcarindiol is an orally active natural polyacetylene compound exhibiting anti-inflammatory and antiproliferative properties. It inhibits NO production in LPS-induced mouse macrophages, reduces tyrosine phosphorylation of JAK1 and JAK2, and modulates STAT1 nuclear translocation, thereby suppressing iNOS expression.

Smiles

C([C@H](/C=C\CCCCCCC)O)#CC#C[C@H](C=C)O

Molecular Formula

C17H24O2

Molecular Weight

260.37

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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