Zidesamtinib
Product Specifications
CAS Number
2739829-00-4
Target
ROS Kinase
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.9978
Bioactivity
Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors.
Smiles
C(C)N1C2=C(CC=3C(C=4C([C@@H](C)OC=5C=C2C=NC5N)=CC(F)=CC4)=NN(C)N3)C=N1
Molecular Formula
C22H22FN7O
Molecular Weight
419.455
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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