G4/HDAC-IN-1
Product Specifications
Target
DNA/RNA Synthesis, Others, HDAC
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Chromatin/Epigenetic
Bioactivity
G4/HDAC-IN-1, a dual-targeting compound for G4 and HDAC, shows inhibition of intracellular HDAC activity, with an IC50 value of 1.1 μM, and promotes G4 formation. It effectively inhibits proliferation and tumor growth in a TNBC xenograft model, presenting potential for cancer research applications.
Smiles
CN(C)CCCNC(=O)C1=CC=C(C=C1)/C=C/2\CCN3C2=NC4=CC(=C(C=C4C3=O)F)N5CCN(CC5)CCCCCCCC(=O)NO.Cl
Molecular Formula
C36H49ClFN7O4
Molecular Weight
698.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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