Azaphilone-9
Product Specifications
CAS Number
1448460-87-4
Target
Others, HuR
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR) . As HuR-RNA interactions play a critical role in stabilizing oncogenic mRNAs within tumors, Azaphilone-9 exhibits potential in inhibiting cancer cell growth and progression.
Smiles
O=C1C=2C(=C(Br)C(=O)C1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2
Molecular Formula
C21H23BrO5
Molecular Weight
435.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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