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P-CAB agent 2

Product Specifications

CAS Number

1978371-23-1

Target

Others, Potassium Channel

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

P-CAB Agent 2 is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor that effectively inhibits H+/K+-ATPase activity, showing an IC50 value of <100 nM. It also demonstrates inhibition of the hERG potassium channel with an IC50 value of 18.69 M, indicating no acute toxicity. P-CAB Agent 2 effectively curbs histamine-induced gastric acid secretion [1].

Smiles

S(=O)(=O)(N1C(=CC(CNC)=C1)C2=C(F)C=CC=C2)C3=CC(OCCCOC)=CC=C3

Molecular Formula

C22H25FN2O4S

Molecular Weight

432.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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