VEGFR-2-IN-30
Product Specifications
Target
VEGFR|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
VEGFR-2-IN-30, a compound acting primarily as a VEGFR-2 inhibitor (IC50: 66 nM), demonstrates additional inhibitory effects on PDGFR, EGFR, and FGFR1, with IC50 values of 180, 98, and 82 nM, respectively. It effectively arrests cancer cells in the S-phase and induces both early and late apoptosis.
Smiles
C1=CC=C(C=C1)CCN2C(=O)C3=CC=CC=C3N=C2SCC(=O)NC4=CC=C(C=C4)S(=O)(=O)NC5=NN=C(C=C5)Cl
Molecular Formula
C28H23ClN6O4S2
Molecular Weight
607.1
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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P4296-06C-ML750 100 µL
PML, Sumoylation Site (Probable Transcription Factor PML, Tripartite Motif-containing Protein 19, RING Finger Protein 71, MYL, RNF71, TRIM19) (MaxLight 750) discontinued
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