Akt1&PKA-IN-1
Product Specifications
CAS Number
1334107-58-2
Target
Akt, PKA, Others, CDK
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Others
Bioactivity
Akt1&PKA-IN-1 is a potent dual inhibitor of Akt and PKA, with IC50 values of 0.11 μM for Akt, 0.03 μM for PKAα, and 9.8 μM for CDK2, demonstrating selective inhibition of cyclin-dependent kinase 2 (CDK2) .
Smiles
[C@@H](NC(=O)C1=CC2=C(C=C1)C=NC=C2)(C3=CC(Cl)=C(Cl)C=C3)C4CNC4
Molecular Formula
C20H17Cl2N3O
Molecular Weight
386.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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