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PARP-2/1-IN-2

Product Specifications

CAS Number

912444-01-0

Target

Others, PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic, Others

Bioactivity

PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].

Smiles

C(N)(=O)C1=C2C(N=C(N2)[C@]3(C)CCCN3)=CC=C1

Molecular Formula

C13H16N4O

Molecular Weight

244.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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