PARP-2/1-IN-2
Product Specifications
CAS Number
912444-01-0
Target
Others|||PARP
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Others
Bioactivity
PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].
Smiles
C(N)(=O)C1=C2C(N=C(N2)[C@]3(C)CCCN3)=CC=C1
Molecular Formula
C13H16N4O
Molecular Weight
244.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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