(6R) -ML753286
Product Specifications
Target
BCRP, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
' (6R) -ML753286, an isomer of ML753286, is an orally active, selective Breast Cancer Resistance Protein (BCRP) inhibitor, demonstrating an IC50 of 0.6 μM. It exhibits high permeability and low to medium clearance in rodent and human liver S9 fractions, with cross-species plasma stability [1].'
Smiles
C[C@H]1C(N2[C@@H](C(N1)=O)CC3=C(NC4=C3C=CC(OC)=C4)[C@H]2CC(C)C)=O
Molecular Formula
C20H25N3O3
Molecular Weight
355.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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