EGFR/HER2-IN-9
Product Specifications
CAS Number
1637253-79-2
Target
EGFR|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling|||Others
Bioactivity
EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR T790M mutation.
Smiles
N(C=1C2=C(C=C(OC)C(NC(/C=C/CN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=O)=C2)N=CN1)C5=CC(Cl)=C(F)C=C5
Molecular Formula
C25H25ClFN5O4
Molecular Weight
513.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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