MDM2-p53-IN-16
Product Specifications
CAS Number
1917350-09-4
Target
Others, MDM-2/p53
Related Pathways
Others, Apoptosis
Bioactivity
MDM2-p53-IN-16 is a potent inhibitor of the MDM2-p53 complex, with an IC 50 value of 4.3 nM for the dissociation of the human p53/MDM2 complex. It effectively reactivates p53, leading to apoptosis and cell-cycle arrest in Glioblastoma Multiforme (GBM) cells, positioning it as a valuable agent for cancer research.
Smiles
C(C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(OC)=O)CC(C)C)=O)=O)(=O)C2=C(NC=3C2=CC=CC3)C4=CC=CC=C4
Molecular Formula
C32H33N3O5
Molecular Weight
539.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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