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E7766 disodium

Product Specifications

CAS Number

2242636-28-6

Target

Others, STING

Related Pathways

Immunology/Inflammation, Others

Bioactivity

E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.

Smiles

O=[P@@](OC[C@@H]1[C@@H](O2)[C@@H](F)[C@H]([N@@]3C=NC(C3=NC=N4)=C4NC/C=C/CN5)O1)(O[C@H]([C@H]6CO[P@@]2([S-])=O)[C@@H](F)[C@@H](O6)[N@]7C8=NC=NC5=C8N=C7)[S-].[Na+].[Na+]

Molecular Formula

C24H26F2N10Na2O8P2S2

Molecular Weight

792.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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