C-Met/HDAC-IN-3
Product Specifications
CAS Number
2439175-23-0
Target
Others, c-Met/HGFR, Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Others
Bioactivity
C-Met/HDAC-IN-3, a dual inhibitor targeting both c-Met and HDAC, exhibits potent inhibitory activity with IC50 values of 12.50 nM for c-Met and 26.97 nM for HDAC1. It induces apoptosis and causes cell cycle arrest in the G2/M phase.
Smiles
O(C=1C2=C(C=C(OCCCCCCC(NO)=O)C(OC)=C2)N=CC1)C3=CC=C(NC(=O)C4C(=O)N(CC4)C5=CC=C(F)C=C5)C=C3
Molecular Formula
C34H35FN4O7
Molecular Weight
630.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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