8-Azanebularine
Product Specifications
CAS Number
38874-46-3
Target
Adenosine Deaminase|||Others
Related Pathways
Metabolism|||Others
Bioactivity
8-Azanebularine, a chemical compound substituting hydrogen for the C6 amino group, effectively inhibits the ADAR2 reaction at elevated concentrations (IC50=15 mM), and exhibits high-affinity binding (KD=2 nM) when incorporated into an RNA structure recognized by human ADAR2. This characteristic makes 8-Azanebularine valuable for researching the ADAR-catalyzed RNA-editing reaction.
Smiles
O[C@H]1[C@H](N2C=3C(N=N2)=CN=CN3)O[C@H](CO)[C@H]1O
Molecular Formula
C9H11N5O4
Molecular Weight
253.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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