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8-Azanebularine

Product Specifications

CAS Number

38874-46-3

Target

Adenosine Deaminase|||Others

Related Pathways

Metabolism|||Others

Bioactivity

8-Azanebularine, a chemical compound substituting hydrogen for the C6 amino group, effectively inhibits the ADAR2 reaction at elevated concentrations (IC50=15 mM), and exhibits high-affinity binding (KD=2 nM) when incorporated into an RNA structure recognized by human ADAR2. This characteristic makes 8-Azanebularine valuable for researching the ADAR-catalyzed RNA-editing reaction.

Smiles

O[C@H]1[C@H](N2C=3C(N=N2)=CN=CN3)O[C@H](CO)[C@H]1O

Molecular Formula

C9H11N5O4

Molecular Weight

253.21

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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