(R) -JAK2/STAT3-IN-10a
Product Specifications
CAS Number
2485758-49-2
Target
Antiviral, Apoptosis
Related Pathways
Immunology/Inflammation, Apoptosis
Purity
0.9834
Bioactivity
(R) -JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R) -JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
Smiles
C(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6
Molecular Formula
C34H35BrF3N5O2
Molecular Weight
682.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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