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(R) -JAK2/STAT3-IN-10a

Product Specifications

CAS Number

2485758-49-2

Target

Antiviral, Apoptosis

Related Pathways

Immunology/Inflammation, Apoptosis

Purity

0.9834

Bioactivity

(R) -JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R) -JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.

Smiles

C(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6

Molecular Formula

C34H35BrF3N5O2

Molecular Weight

682.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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