PD-1/PD-L1-IN-29
Product Specifications
CAS Number
2665734-13-2
Target
Others|||PD-1/PD-L1
Related Pathways
Others|||Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation
Bioactivity
PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction with an IC50 value of 6.1 nM. It effectively binds to PD-L1, promoting its dimerization and internalization, enhancing its localization to the endoplasmic reticulum, and demonstrating anticancer activity.
Smiles
O=C1N(C(=O)C=2C1=CC(CN[C@H](C(O)=O)CO)=C(OC)C2)C3=C(C)C(=CC=C3)C4=CC=CC=C4
Molecular Formula
C26H24N2O6
Molecular Weight
460.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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