PD-1/PD-L1-IN-23
Product Specifications
CAS Number
2597056-04-5
Target
PD-1/PD-L1, Others
Related Pathways
Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint, Others
Bioactivity
PD-1/PD-L1-IN-23 is a potent, orally active ester prodrug of L7, a benzooxadiazole derivative, that functions as an inhibitor of PD-1/PD-L1. It has undergone biological evaluation for its inhibitory effects on PD-L1, showing significant antitumor effects in both syngeneic tumor models and PD-L1 humanized mice.
Smiles
O(CC1=CC=2C(C=C1)=NON2)C3=C(CN[C@@H](C(OCC)=O)CO)C=C(Cl)C(OCC4=C(Br)C(=CC=C4)C5=CC=CC=C5)=C3.Cl
Molecular Formula
C32H30BrCl2N3O6
Molecular Weight
703.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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