PD-1/PD-L1-IN-26
Product Specifications
CAS Number
2966090-78-6
Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis
Bioactivity
PD-1/PD-L1-IN-26 (Compound II-14) is a potent PD-1/PD-L1 inhibitor with an IC50 of 0.0380 μM. It enhances the immune microenvironment by promoting CD4+ T cell infiltration into tumor tissues, suggesting its potential application in cancer research [1].
Smiles
CC1=C(C=CC=C1C2=CC(=CC=C2)OCCCN3CCC(CC3)CO)COC4=CC(=C(C=C4)CNC(CO)(CO)CO)OCC5=NN=C(O5)C6=CC=CC=C6
Molecular Formula
C43H52N4O8
Molecular Weight
752.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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