Nampt activator-3
Product Specifications
CAS Number
2790481-63-7
Target
NAMPT|||Others
Related Pathways
Others|||Metabolism
Bioactivity
NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 ?M and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].
Smiles
O(CC(NC1=CC=C(O)C=C1)=O)C2=C(C(C)(C)C)C=CC=C2C#N
Molecular Formula
C19H20N2O3
Molecular Weight
324.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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