GCGR antagonist 2
Product Specifications
CAS Number
280134-25-0
Target
Glucagon Receptor, Others
Related Pathways
Others, GPCR/G Protein
Bioactivity
GCGR Antagonist 2, a Furan-2-carbohydrazide, serves as an orally active antagonist of the glucagon receptor. It exhibits affinity for the human glucagon receptor (hGluR) with a dissociation constant (Kd) of 2.3 nM and demonstrates inhibitory activity against the rat receptor with a half-maximal inhibitory concentration (IC50) of 0.43 nM. Additionally, this compound effectively prevents glucagon-stimulated glycogenolysis.
Smiles
C(N1C=2C(=C(C=NNC(=O)C3=CC(C#N)=C(O)C=C3)C=CC2)C=C1)C4=C(C)C(C)=CC(C)=C4C
Molecular Formula
C28H26N4O2
Molecular Weight
450.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUM2598-50 1x 50 µL
CD34 (Hematopoietic Stem Cell & Endothelial Marker) (HPCA1/2598R), 1mg/mL
Sign In for Pricing
View Details ![RFC3 Mouse Monoclonal Antibody [Clone ID: OTI4A7]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908c34/imageurl/cf811875.webp)
TRC-D943845-0.5MG 0.5 mg
10Beta-Hydroxyl Dextrorphan 3-O-Beta-D-Glucuronide
Sign In for Pricing
View Details 