What is the catalog number for Broussochalcone A?

The catalog number for Broussochalcone A is T72594.

What sizes are available for Broussochalcone A?

Broussochalcone A is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does Broussochalcone A come in?

Broussochalcone A is available in 4 different pack sizes.

Is Broussochalcone A in stock?

Broussochalcone A is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Broussochalcone A?

Broussochalcone A is manufactured by Molfinity.

What is the estimated delivery time for Broussochalcone A?

Estimated delivery time for Broussochalcone A is approximately 10 business day(s), depending on your location.

Broussochalcone A

Product Specifications

CAS Number

99217-68-2

Target

Reactive Oxygen Species, Apoptosis, NR4A, FOXO, ROS, Xanthine Oxidase

Related Pathways

NF-κB, Apoptosis, Endocrinology/Hormones, Immunology/Inflammation, Metabolism

Purity

0.9746

Bioactivity

Broussochalcone A is a natural antioxidant and xanthine oxidase inhibitor (IC50 = 2.21 μM) that scavenges free radicals, inhibits iron-induced lipid peroxidation, and reduces nitric oxide synthesis in LPS-activated macrophages. Broussochalcone A induces apoptosis in human renal carcinoma cells by increasing ROS levels and activating the FOXO3 signaling pathway. Broussochalcone A is also a novel NR4A1 inhibitor that induces apoptosis in pancreatic cancer cells through NR4A1-dependent pathways.