Lapatinib tosylate
Product Specifications
CAS Number
1187538-35-7
Target
Autophagy, EGFR, Ferroptosis, Others
Related Pathways
Apoptosis, JAK/STAT signaling, Autophagy, Angiogenesis, Others, Tyrosine Kinase/Adaptors
Bioactivity
Lapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
Smiles
O=S(=O)(O)C1=CC=C(C=C1)C.O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2
Molecular Formula
C36H34ClFN4O7S2
Molecular Weight
753.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![SOX6 Mouse Monoclonal Antibody [Clone ID: OTI1E7]](https://cdn.genprice.uk/products/937/68dd18ba061270361e90845c/imageurl/cf808919.webp)
![SQSTM1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A7]](https://cdn.genprice.uk/products/937/68dd1b68061270361ea156d4/imageurl/ta502239am.webp)
TA502239AM 100 µL
SQSTM1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A7]
Sign In for Pricing
View Details 