HIV-1 inhibitor-52

Product Specifications

CAS Number

1818868-23-3

Target

HIV Protease|||Others

Related Pathways

Microbiology/Virology|||Others|||Proteases/Proteasome

Bioactivity

HIV-1 inhibitor-52 is a powerful inhibitor of a broad spectrum of HIV-1 activities, demonstrating effectiveness with EC50 values ranging from 1.6 nM to 6.4 nM against various strains, including [WT HIV-1], [HIV-1 V370A], [HIV-1 ?V370], [HIV-1 V362I/V370A], [HIV-1 T332S/V362I/prR41G], [HIV-1 A326T/V362I/V370A], and [HIV-1 R361K/V362I/L363M].

Smiles

N(CC[C@@]1(O)CC[C@H](S(C)(=O)=O)CC1)[C@@]23[C@@]([C@@]4([C@@](C)(CC2)[C@@]5(C)[C@](CC4)([C@]6(C)[C@@](CC5)(C(C)(C)C(=CC6)C=7CC[C@](C(O)=O)(CF)CC7)[H])[H])[H])([C@H](C(C)=C)CC3)[H]