IGUANA-1 free base
Product Specifications
CAS Number
2756014-24-9
Target
Others, Dehydrogenase
Related Pathways
Others, Metabolism
Bioactivity
IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor with an IC50 value of 30 nM, and efficaciously inhibits the growth of SW480 cells in both adherent and spheroid conditions, yielding IC50 values of 2.46 μM and 0.39 μM, respectively; this compound is utilized in cancer research.
Smiles
ClC=1C=CC(=C(OC)C1)C2=CN(C=3C=CC(=CC3)C=4C=CC=CC4OC)C5=NCCCN52
Molecular Formula
C26H24ClN3O2
Molecular Weight
445.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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