Efflux inhibitor-1
Product Specifications
CAS Number
1776055-29-8
Target
Others, BCRP
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC 50 s of 0.45 μM and 2.17 μM, respectively .
Smiles
O(C)C1=C(C2=NN3C(=CC(=NC3=C2)C4=CC=CC=C4)N5CCN(C(=O)C=6C=COC6)CC5)C=CC=C1
Molecular Formula
C28H25N5O3
Molecular Weight
479.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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