Niclosamide sodium
Product Specifications
CAS Number
40321-86-6
Target
Antibiotic, Others, STAT, Parasite
Related Pathways
Microbiology/Virology, JAK/STAT signaling, Others, Stem Cells
Bioactivity
Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compound exhibits significant biological activities against cancer and effectively inhibits DNA replication in Vero E6 cells.
Smiles
O=[N+]([O-])C1=CC(Cl)=C(NC(C2=C([O-])C=CC(Cl)=C2)=O)C=C1.[Na+]
Molecular Formula
C13H7Cl2N2NaO4
Molecular Weight
349.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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