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Elobixibat hydrate

Product Specifications

CAS Number

1633824-78-8

Target

Others, ASBT

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

Elobixibat hydrate, a potent inhibitor of the ileal bile acid transporter (IBAT), exhibits IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human, mouse, and canine IBAT, respectively. It is utilized in the research of chronic idiopathic constipation (CIC) .

Smiles

O=S1(=O)C=2C(N(CC(CCCC)(CCCC)C1)C3=CC=CC=C3)=CC(SC)=C(OCC(N[C@@H](C(NCC(O)=O)=O)C4=CC=CC=C4)=O)C2.O

Molecular Formula

C36H47N3O8S2

Molecular Weight

713.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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