THZ1 Hydrochloride
Product Specifications
Target
Others, CDK
Related Pathways
Others, Cell Cycle/Checkpoint
Bioactivity
THZ1 Hydrochloride is a potent, selective covalent inhibitor of CDK7, exhibiting an IC50 value of 3.2 nM. It also targets closely related kinases CDK12 and CDK13, leading to the downregulation of MYC expression.
Smiles
CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl.Cl
Molecular Formula
C31H29Cl2N7O2
Molecular Weight
602.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
Z0510-12A 50 µg
SLC39A10, ID (Zinc Transporter ZIP10, Solute Carrier Family 39 Member 10, Zrt- and Irt-like Protein 10, ZIP-10, KIAA1265, ZIP10) discontinued
Sign In for Pricing
View Details 
MBS7010428-01 0.02 mg
Recombinant Pongo abelii Bladder cancer-associated protein (BLCAP)
Sign In for Pricing
View Details MBS7010428-02 0.1 mg
Recombinant Pongo abelii Bladder cancer-associated protein (BLCAP)
Sign In for Pricing
View Details 
MBS7010428-03 5x 0.1 mg
Recombinant Pongo abelii Bladder cancer-associated protein (BLCAP)
Sign In for Pricing
View Details