THZ1 Hydrochloride
Product Specifications
Target
Others|||CDK
Related Pathways
Others|||Cell Cycle/Checkpoint
Bioactivity
THZ1 Hydrochloride is a potent, selective covalent inhibitor of CDK7, exhibiting an IC50 value of 3.2 nM. It also targets closely related kinases CDK12 and CDK13, leading to the downregulation of MYC expression.
Smiles
CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl.Cl
Molecular Formula
C31H29Cl2N7O2
Molecular Weight
602.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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