(+) -Norfenfluramine
Product Specifications
CAS Number
19036-73-8
Target
5-HT Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
(+) -Norfenfluramine, the principal hepatic metabolite of (+) -fenfluramine, acts as a selective agonist for the 5-HT2B receptor, exhibiting a potent K i of 11.2 nM. It significantly promotes the hydrolysis of inositol phosphates and heightens intracellular Ca2+ levels. This compound is valuable in the study of primary pulmonary hypertension and valvular heart disease.
Smiles
C[C@H](N)Cc1cccc(c1)C(F)(F)F
Molecular Formula
C10H12F3N
Molecular Weight
203.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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