Aurora Kinases-IN-3

Product Specifications

CAS Number

2840558-83-8

Target

PLK|||Aurora Kinase|||Others

Related Pathways

Others|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint

Bioactivity

Aurora Kinases-IN-3, an orally active inhibitor of AURKB, suppresses AURKB activity by hindering its mitotic localization rather than by inhibiting its phosphorylation of H3 at Ser10.

Smiles

O(C1=C(C=CC=N1)C=2C=C(OC)N=CC2)C3=CC(C(NC)=O)=CC(OC(F)(F)F)=C3

Molecular Formula

C20H16F3N3O4

Molecular Weight

419.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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