PI3K/mTOR Inhibitor-12
Product Specifications
CAS Number
2891692-83-2
Target
MTOR, PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PI3K/mTOR Inhibitor-12, a potent and selective orally active inhibitor, exhibits IC50 values of 0.06 nM for PI3Kα and 3.12 nM for mTOR, indicating significant antitumor activity with reduced liver toxicity [1].
Smiles
COC1=C(C=C(C=N1)C2=NN3C(=NC=C3C4=CN(N=N4)CCCN5CCOCC5)C=C2)NS(=O)(=O)C6=C(C=C(C=C6)F)F
Molecular Formula
C27H27F2N9O4S
Molecular Weight
611.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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