KRAS G12D inhibitor 16
Product Specifications
CAS Number
2648221-12-7
Target
Ras, Kras, Others
Related Pathways
Others, MAPK, GPCR/G Protein
Bioactivity
KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant tumors including pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), and non-small cell lung carcinomas (NSCLC) .
Smiles
C(C1(COC2=NC(=C3C(=N2)CN(CC3)C=4C5=C(C=C(O)C4)C=CC=C5I)N6CC7NC(C6)CC7)CC1)N8CCOCC8
Molecular Formula
C32H39IN6O3
Molecular Weight
682.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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