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R 59-022 hydrochloride

Product Specifications

CAS Number

93076-98-3

Target

PKC, 5-HT Receptor

Related Pathways

Neuroscience, GPCR/G Protein, Cytoskeletal Signaling, Chromatin/Epigenetic

Purity

0.9833

Bioactivity

R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC) .R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 μM) that inhibits the phosphorylation of OAG to OAPA.R 59-022 enhances thrombin-induced triglyceride production in platelets and inhibits the production of phosphatidic acid in neutrophils. R 59-022 enhances thrombin-induced diglyceride production in platelets and inhibits phosphatidic acid production in neutrophils.

Smiles

Cl.O=C1C(=C(N=C2SC=CN21)C)CCN3CCC(=C(C=4C=CC=CC4)C5=CC=C(F)C=C5)CC3

Molecular Formula

C27H27ClFN3OS

Molecular Weight

496.04

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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