R 59-022 hydrochloride
Product Specifications
CAS Number
93076-98-3
Target
PKC|||5-HT Receptor
Related Pathways
Neuroscience|||GPCR/G Protein|||Cytoskeletal Signaling|||Chromatin/Epigenetic
Purity
0.9833
Bioactivity
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC) .R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R 59-022 enhances thrombin-induced triglyceride production in platelets and inhibits the production of phosphatidic acid in neutrophils. R 59-022 enhances thrombin-induced diglyceride production in platelets and inhibits phosphatidic acid production in neutrophils.
Smiles
Cl.O=C1C(=C(N=C2SC=CN21)C)CCN3CCC(=C(C=4C=CC=CC4)C5=CC=C(F)C=C5)CC3
Molecular Formula
C27H27ClFN3OS
Molecular Weight
496.04
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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