CEP-28122 mesylate salt
Product Specifications
Target
Others|||ALK
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Others
Bioactivity
CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) inhibitor with an IC50 value of 1.9 nM against recombinant ALK kinase activity. It shows antitumor efficacy in ALK-positive human cancer models and has favorable pharmacodynamic and pharmacokinetic profiles.
Smiles
COC1=C(C=CC2=C1CC[C@H](CC2)N3CCOCC3)NC4=NC=C(C(=N4)N[C@@H]5[C@@H]6C[C@H]([C@@H]5C(=O)N)C=C6)Cl.CS(=O)(=O)O
Molecular Formula
C29H39ClN6O6S
Molecular Weight
635.17
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rat Monoclonal IL-15 R alpha Antibody (RM0103-6C38) [DyLight 650]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP1-22466C 0.1 mL
Rat Monoclonal IL-15 R alpha Antibody (RM0103-6C38) [DyLight 650]
Ask
View Details 
048957-AF-01 200 µg
IGF-I, LR3, Recombinant, Human (Insulin-like Growth Factor-I Long R3, Somatamedin C, IGF-IA) (Animal Free)
Ask
View Details 048957-AF-02 1 mg
IGF-I, LR3, Recombinant, Human (Insulin-like Growth Factor-I Long R3, Somatamedin C, IGF-IA) (Animal Free)
Ask
View Details